Publications | Department of Population Medicine

High-dimensional multiple imputation (HDMI) for partially observed confounders including natural language processing-derived auxiliary covariates. (Pubmed Abstract)

Authors

Weberpals J, Shaw PA, Lin KJ, Wyss R, Plasek JM, Zhou L, Ngan K, DeRamus T, Raman SR, Hammill BG, Lee H, Toh S, Connolly JG, Dandreo KJ, Tian F, Liu W, Li J, Hernández-Muñoz JJ, Schneeweiss S, Desai RJ

Abbreviation

Am J Epidemiol

Publication Date

2025-01-22

Real-World Effectiveness of Bebtelovimab Versus Nirmatrelvir/Ritonavir in Outpatients with COVID-19. (Pubmed Abstract)

Authors

Rowan CG, Nichols RM, Dhopeshwarkar N, Alyea JM, Zhu B, Toh S, Chan KA, Grace EL

Abbreviation

Pulm Ther

Publication Date

2024-12-25

Peer Review of Real-World Data Studies and Open Science-Connecting the Last Mile. (Pubmed Abstract)

Authors

Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Volume

Issue

Publication Date

2024-11-07

Considerations Regarding Association of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy. (Pubmed Abstract)

Authors

Maro JC, Platt R, Toh S

Abbreviation

JAMA Ophthalmol

Publication Date

2024-10-31

Analyzing missingness patterns in real-world data using the SMDI toolkit: application to a linked EHR-claims pharmacoepidemiology study. (Pubmed Abstract)

Authors

Raman SR, Hammill BG, Shaw PA, Lee H, Toh S, Connolly JG, Dandreo KJ, Nalawade V, Tian F, Liu W, Li J, Hernández-Muñoz JJ, Glynn RJ, Desai RJ, Weberpals J

Abbreviation

BMC Med Res Methodol

Volume

Issue

Publication Date

2024-10-19

Tree-based scan statistics to generate drug repurposing hypotheses: a test case using sodium-glucose cotransporter-2 inhibitors. (Pubmed Abstract)

Authors

Tan GSQ, Maro JC, Wang SV, Toh S, Morton JI, Ilomäki J, Wong J, Li X

Abbreviation

Am J Epidemiol

Publication Date

2024-09-11

A Distributed Regression Analysis Application Package Using SAS (View Abstract)

Authors

Qoua L. Her, Dongdong Li, Yury Vilk, Jessica Young, Zilu Zhang, Jessica M. Malenfant, Sarah Malek & Sengwee Toh

Publication Date

2024-07-09

A simple Cox approach to estimating risk ratios without sharing individual-level data in multi-site studies. (Pubmed Abstract)

Authors

Shu D, Zou G, Hou L, Petrone AB, Maro JC, Fireman BH, Toh S, Connolly JG

Abbreviation

Am J Epidemiol

Publication Date

2024-07-05

Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study. (Pubmed Abstract)

Authors

Petimar J, Young JG, Yu H, Rifas-Shiman SL, Daley MF, Heerman WJ, Janicke DM, Jones WS, Lewis KH, Lin PD, Prentice C, Merriman JW, Toh S, Block JP

Abbreviation

Ann Intern Med

Publication Date

2024-07-02

Use of the Sentinel System to Examine Medical Product Use and Outcomes During Pregnancy. (Pubmed Abstract)

Authors

Lyons JG, Shinde MU, Maro JC, Petrone A, Cosgrove A, Kempner ME, Andrade SE, Mwidau J, Stojanovic D, Hernández-Muñoz JJ, Toh S

Abbreviation

Drug Saf

Publication Date

2024-06-28

Transparency, reproducibility, and replicability of pharmacoepidemiology studies in a distributed network environment. (Pubmed Abstract)

Authors

Rai A, Maro JC, Dutcher S, Bright P, Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Volume

Issue

Publication Date

2024-05-25

A Principled Approach to Characterize and Analyze Partially Observed Confounder Data from Electronic Health Records. (Pubmed Abstract)

Authors

Weberpals J, Raman SR, Shaw PA, Lee H, Russo M, Hammill BG, Toh S, Connolly JG, Dandreo KJ, Tian F, Liu W, Li J, Hernández-Muñoz JJ, Glynn RJ, Desai RJ

Abbreviation

Clin Epidemiol

Volume

Publication Date

2024-05-21

Using Claims Data to Predict Pre-Operative BMI Among Bariatric Surgery Patients: Development of the BMI Before Bariatric Surgery Scoring System (B3S3). (Pubmed Abstract)

Authors

Wong J, Li X, Arterburn DE, Li D, Messenger-Jones E, Wang R, Toh S

Abbreviation

Pragmat Obs Res

Volume

Publication Date

2024-03-27

Targeted Learning with an Undersmoothed Lasso Propensity Score Model for Large-Scale Covariate Adjustment in Healthcare Database Studies. (Pubmed Abstract)

Authors

Wyss R, van der Laan M, Gruber S, Shi X, Lee H, Dutcher SK, Nelson JC, Toh S, Russo M, Wang SV, Desai RJ, Lin KJ

Abbreviation

Am J Epidemiol

Publication Date

2024-03-21

Process guide for inferential studies using healthcare data from routine clinical practice to evaluate causal effects of drugs (PRINCIPLED): considerations from the FDA Sentinel Innovation Center. (Pubmed Abstract)

Authors

Desai RJ, Wang SV, Sreedhara SK, Zabotka L, Khosrow-Khavar F, Nelson JC, Shi X, Toh S, Wyss R, Patorno E, Dutcher S, Li J, Lee H, Ball R, Dal Pan G, Segal JB, Suissa S, Rothman KJ, Greenland S, Hernán MA, Heagerty PJ, Schneeweiss S

Abbreviation

BMJ

Volume

384

Publication Date

2024-02-12

smdi: an R package to perform structural missing data investigations on partially observed confounders in real-world evidence studies. (Pubmed Abstract)

Authors

Weberpals J, Raman SR, Shaw PA, Lee H, Hammill BG, Toh S, Connolly JG, Dandreo KJ, Tian F, Liu W, Li J, Hernández-Muñoz JJ, Glynn RJ, Desai RJ

Abbreviation

JAMIA Open

Volume

Issue

Publication Date

2024-01-31

Predicting risk of suicidal behavior from insurance claims data vs. linked data from insurance claims and electronic health records. (Pubmed Abstract)

Authors

Simon GE, Shortreed SM, Johnson E, Yaseen ZS, Stone M, Mosholder AD, Ahmedani BK, Coleman KJ, Coley RY, Penfold RB, Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2023-12-19

Data-driven automated classification algorithms for acute health conditions: applying PheNorm to COVID-19 disease. (Pubmed Abstract)

Authors

Smith JC, Williamson BD, Cronkite DJ, Park D, Whitaker JM, McLemore MF, Osmanski JT, Winter R, Ramaprasan A, Kelley A, Shea M, Wittayanukorn S, Stojanovic D, Zhao Y, Toh S, Johnson KB, Aronoff DM, Carrell DS

Abbreviation

J Am Med Inform Assoc

Publication Date

2023-12-18

Association Between Use of Fluoroquinolones and Risk of Mitral or Aortic Valve Regurgitation: A Nationwide Cohort Study. (Pubmed Abstract)

Authors

Dong YH, Wang JL, Chang CH, Lin JW, Chen YA, Chen CY, Toh S

Abbreviation

Clin Pharmacol Ther

Publication Date

2023-11-05

Corticosteroids but not Anti-TNF Are Associated With Increased COVID-19 Complications in Patients With Inflammatory Bowel Disease. (Pubmed Abstract)

Authors

Long MD, Parlett L, Lewis JD, Haynes K, Adimadhyam S, Hou L, Wolfe A, Toh S, Burris J, Dorand J, Kappelman MD

Abbreviation

Inflamm Bowel Dis

Publication Date

2023-08-23

Combining meta-analysis with multiple imputation for one-step, privacy-protecting estimation of causal treatment effects in multi-site studies. (Pubmed Abstract)

Authors

Shu D, Li X, Her Q, Wong J, Li D, Wang R, Toh S

Abbreviation

Res Synth Methods

Volume

Issue

Publication Date

2023-08-01

External validity in distributed data networks. (Pubmed Abstract)

Authors

Webster-Clark M, Toh S, Arnold J, McTigue KM, Carton T, Platt R

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2023-07-18

Utilization, user characteristics, and adverse outcomes of insulin glargine originators and follow-on drug in patients with diabetes in the United States. (Pubmed Abstract)

Authors

Rai A, Nam YH, Mendelsohn AB, Marshall J, McDermott CL, Toh S, Lockhart CM

Abbreviation

J Manag Care Spec Pharm

Volume

Issue

Publication Date

2023-07-06

Distributed Cox proportional hazards regression using summary-level information. (Pubmed Abstract)

Authors

Li D, Lu W, Shu D, Toh S, Wang R

Abbreviation

Biostatistics

Volume

Issue

Publication Date

2023-07

Real-world Evidence Comparing Tofacitinib and Vedolizumab in Anti-TNF-experienced Patients With Ulcerative Colitis. (Pubmed Abstract)

Authors

Adimadhyam S, Lewis JD, Simon AL, Wolfe AE, Smith S, Hou L, Moyneur É, Reynolds JS, Toh S, Dobes A, Parlett L, Haynes K, Burris J, Dorand JE, Long MD, Kappelman MD

Abbreviation

Inflamm Bowel Dis

Publication Date

2023-06-26

Preoperative Depression Status and 5 Year Metabolic and Bariatric Surgery Outcomes in the PCORnet Bariatric Study Cohort (Pubmed Abstract)

Publication Date

2023-04-01

Imputing Missing Covariates in Time-to-event Analysis within Distributed Research Networks: A Simulation Study. (Pubmed Abstract)

Authors

Li D, Wong J, Li X, Toh S, Wang R

Abbreviation

Pharmacoepidemiol Drug Saf

Volume

Issue

Publication Date

2023-03

Association Between Regular Laxative Use and Incident Dementia in UK Biobank Participants. (Pubmed Abstract)

Authors

Yang Z, Wei C, Li X, Yuan J, Gao X, Li B, Zhao Z, Toh S, Yu X, Brayne C, Yang Z, Sha F, Tang J

Abbreviation

Neurology

Publication Date

2023-02-22

The Authors' Reply: Statins and post-stroke dementia. (Pubmed Abstract)

Authors

Yang Z, Toh S, Mant J

Abbreviation

Eur J Epidemiol

Publication Date

2023-01-11

Using the IMEDS distributed database for epidemiological studies in type 2 diabetes mellitus. (Pubmed Abstract)

Authors

Huang TY, Rodriguez-Watson C, Wang T, Calhoun SR, Marshall J, Burk J, Nam YH, Mendelsohn AB, Jamal-Allial A, Greenlee RT, Selvan M, Pawloski PA, McMahill Walraven CN, Rai A, Toh S, Brown JS

Abbreviation

BMJ Open Diabetes Res Care

Volume

Issue

Publication Date

2022-12-21

Assessing the impact of privacy-preserving record linkage on record overlap and patient demographic and clinical characteristics in PCORnet®, the National Patient-Centered Clinical Research Network. (Pubmed Abstract)

Authors

Marsolo K, Kiernan D, Toh S, Phua J, Louzao D, Haynes K, Weiner M, Angulo F, Bailey C, Bian J, Fort D, Grannis S, Krishnamurthy AK, Nair V, Rivera P, Silverstein J, Zirkle M, Carton T

Abbreviation

J Am Med Inform Assoc

Publication Date

2022-11-30

Real-World Evidence Comparing Vedolizumab and Ustekinumab in Antitumor Necrosis Factor-Experienced Patients With Crohn's Disease. (Pubmed Abstract)

Authors

Kappelman MD, Adimadhyam S, Hou L, Wolfe AE, Smith S, Simon AL, Moyneur É, Reynolds JS, Toh S, Dobes A, Parlett LE, Haynes K, Selvan M, Ma Q, Nair V, Burris J, Dorand JE, Dawwas GK, Lewis JD, Long MD

Abbreviation

Am J Gastroenterol

Publication Date

2022-11-23

Assessing medical product safety during pregnancy using parameterizable tools in the sentinel distributed database. (Pubmed Abstract)

Authors

Lyons JG, Suarez EA, Fazio-Eynullayeva E, Maro JC, Corey C, Li J, Toh S, Shinde MU

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2022-11-09

High-dimensional propensity scores for empirical covariate selection in secondary database studies: planning, implementation, and reporting. (Pubmed Abstract)

Authors

Rassen JA, Blin P, Kloss S, Neugebauer RS, Platt RW, Pottegård A, Schneeweiss S, Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2022-11-08

Establishing a framework for privacy-preserving record linkage among electronic health record and administrative claims databases within PCORnet, the National Patient-Centered Clinical Research Network. (Pubmed Abstract)

Authors

Kiernan D, Carton T, Toh S, Phua J, Zirkle M, Louzao D, Haynes K, Weiner M, Angulo F, Bailey C, Bian J, Fort D, Grannis S, Krishnamurthy AK, Nair V, Rivera P, Silverstein J, Marsolo K

Abbreviation

BMC Res Notes

Volume

Issue

Publication Date

2022-10-31

The US Food and Drug Administration Sentinel System: a national resource for a learning health system. (Pubmed Abstract)

Authors

Brown JS, Mendelsohn AB, Nam YH, Maro JC, Cocoros NM, Rodriguez-Watson C, Lockhart CM, Platt R, Ball R, Dal Pan GJ, Toh S

Abbreviation

J Am Med Inform Assoc

Publication Date

2022-09-12

Comparative Safety and Effectiveness of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy for Weight Loss and Type 2 Diabetes Across Race and Ethnicity in the PCORnet Bariatric Study Cohort. (Pubmed Abstract)

Authors

Coleman KJ, Wellman R, Fitzpatrick SL, Conroy MB, Hlavin C, Lewis KH, Coley RY, McTigue KM, Tobin JN, McBride CL, Desai JR, Clark JM, Toh S, Sturtevant JL, Horgan CE, Duke MC, Williams N, Anau J, Horberg MA, Michalsky MP, Cook AJ, Arterburn DE, Apovian CM,

Abbreviation

JAMA Surg

Publication Date

2022-08-31

Meta-analysis with sample-standardization in multi-site studies. (Pubmed Abstract)

Authors

Shu D, Webster-Clark M, Platt RW, Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2022-08-17

Can Observational Analyses of Routinely Collected Data Emulate Randomized Trials? Design and Feasibility of the Observational Patient Evidence for Regulatory Approval Science and Understanding Disease Project. (Pubmed Abstract)

Authors

Crown W, Dahabreh IJ, Li X, Toh S, Bierer B

Abbreviation

Value Health

Publication Date

2022-08-12

Profiling Real-World Data Sources for Pharmacoepidemiologic Research: A Call for Papers. (Pubmed Abstract)

Authors

Li X, Lo Re V, Toh S

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2022-05-25

Go BIG and Go Global: Executing Large-Scale, Multi-Site Pharmacoepidemiologic Studies Using Real-world Data. (Pubmed Abstract)

Authors

Maro JC, Toh S

Abbreviation

Am J Epidemiol

Publication Date

2022-05-20

Applying Machine Learning in Distributed Data Networks for Pharmacoepidemiologic and Pharmacovigilance Studies: Opportunities, Challenges, and Considerations. (Pubmed Abstract)

Authors

Wong J, Prieto-Alhambra D, Rijnbeek PR, Desai RJ, Reps JM, Toh S

Abbreviation

Drug Saf

Volume

Issue

Publication Date

2022-05-17

Association between glucagon-like peptide-1 receptor agonists and biliary-related diseases in patients with type 2 diabetes: a nationwide cohort study. (Pubmed Abstract)

Authors

Dong YH, Wu JH, Chang CH, Lin JW, Wu LC, Toh S

Abbreviation

Pharmacotherapy

Publication Date

2022-05-04

Comparative cardiovascular effectiveness of glucagon-like peptide-1 receptor agonists versus sodium glucose cotransporter 2 inhibitors in patients with type 2 diabetes: a population-based cohort study. (Pubmed Abstract)

Authors

Dong YH, Chang CH, Lin JW, Yang WS, Wu LC, Toh S

Abbreviation

Diabetes Obes Metab

Publication Date

2022-05-01

Continuity and Completeness of Electronic Health Record Data for Patients Treated With Oral Hypoglycemic Agents: Findings From Healthcare Delivery Systems in Taiwan. (Pubmed Abstract)

Authors

Hsu CN, Huang K, Lin FJ, Ou HT, Huang LY, Kuo HC, Wang CC, Toh S

Abbreviation

Front Pharmacol

Volume

Publication Date

2022-04-04

Comparison of Rates of Type 2 Diabetes in Adults and Children Treated With Anticonvulsant Mood Stabilizers. (Pubmed Abstract)

Authors

Sun JW, Young JG, Sarvet AL, Bailey LC, Heerman WJ, Janicke DM, Lin PD, Toh S, Block JP

Abbreviation

JAMA Netw Open

Volume

Issue

Publication Date

2022-04-01

Statin use is associated with lower risk of dementia in stroke patients: a community-based cohort study with inverse probability weighted marginal structural model analysis. (Pubmed Abstract)

Authors

Yang Z, Toh S, Li X, Edwards D, Brayne C, Mant J

Abbreviation

Eur J Epidemiol

Publication Date

2022-03-19

Use of Linked Databases for Improved Confounding Control: Considerations for Potential Selection Bias. (Pubmed Abstract)

Authors

Sun JW, Wang R, Li D, Toh S

Abbreviation

Am J Epidemiol

Volume

191

Issue

Publication Date

2022-03

Utility of fertility procedures and prenatal tests to estimate gestational age for live-births and stillbirths in electronic health plan databases. (Pubmed Abstract)

Authors

Taylor L, Bird ST, Stojanovic D, Toh S, Maro JC, Fazio-Eynullayeva E, Petrone AB, Rajbhandari R, Andrade SE, Haynes K, McMahill-Walraven CN, Shinde M, Lyons JG

Abbreviation

Pharmacoepidemiol Drug Saf

Publication Date

2022-02-05

Evaluating confounding control in estimations of influenza antiviral effectiveness in electronic health plan data. (Pubmed Abstract)

Authors

Htoo PT, Measer G, Orr R, Bohn J, Sorbello A, Francis H, Dutcher SK, Cosgrove A, Carruth A, Toh S, Cocoros NM

Abbreviation

Am J Epidemiol

Publication Date

2022-02-02