Sexual Orientation and Age at Menarche in Three U.S. Longitudinal Cohorts.

View Abstract

PURPOSE

The aim of this study is to examine age at menarche across sexual orientation groups.

METHODS

Data were obtained from 131,090 female participants, born 1947-2001, in 3 longitudinal studies-the Growing Up Today Study and Nurses' Health Study 2 and 3. We estimated the association between sexual orientation and age at menarche using regression models adjusted for age, race/ethnicity, birthweight, height, and body mass index.

RESULTS

Compared to heterosexual participants, sexual minorities were younger at menarche. Sexual minorities were more likely to have early menarche (≤11 years) and less likely to have late menarche (≥14 years) compared to heterosexual girls. As an example of this pattern, Nurses' Health Study 3 bisexual participants were >30% more likely than heterosexuals to have early versus average menarche (odds ratio 1.37, 95% confidence interval 1.09-1.72).

CONCLUSION

Sexual minority girls have a younger age at menarche than heterosexual girls and may benefit from screening for adverse outcomes associated with early menarche.

Investigators
Abbreviation
J Adolesc Health
Publication Date
2021-08-14
Pubmed ID
34404608
Medium
Print-Electronic
Full Title
Sexual Orientation and Age at Menarche in Three U.S. Longitudinal Cohorts.
Authors
Charlton BM, Carwile JL, Chavarro JE, DiVasta AD, Ziyadeh NJ, Austin SB