CHeRP News Archive: 2023

CHeRP News Archive: 2023

OCTOBER

Congrats to CHeRP fellow Ellen Kim Deluca on winning the Anne Stiggelbout Lusted Award (again) at the 2023 Society of Medical Decision-Making Conference!

Congratulations to Hadley Stevens Smith, the inaugural winner of the Sandy Schwartz Young Scholar Award at the 2023 Society of Medical Decision-Making Conference! This award honors an early career Health Policy and Medical Decision Making scholar with potential for impact and leadership in the field!

Welcome to CHeRP Taylor Montgomery! Taylor Montgomery joined CHeRP as a Senior Research Assistant. Taylor received her BA in Kinesiology Sports Medicine and Philosophy from Rice University in 2022 and received her MPH in Health Services Organization from the University of Texas in 2023. While completing her MPH, Taylor worked as a graduate research intern on the ethical and policy implications of pediatric deep brain stimulation (pDBS) for children with psychiatric disorders. Her research interests include pediatric bioethics and public health ethics and policy. She will be working with Hadley Stevens-Smith on an NIH diversity supplement focused on the ELSI of pediatric genomic sequencing.

Congratulations to Madison (Maddie) Hickingbotham on her well-deserved promotion to Senior Research Assistant!

Cheers to Isdin Oke and Ann Wu for their publication Vision Testing for Adolescents in the US which is featured in JAMA Ophthalmology!

Congrats to Ann and peers for their publication Improving Difficult-to-Treat Asthma With Digital Inhaler Adherence Technologies: Are We There Yet? featured in JACI In Practice!

Cheers to Mei-Sing Ong, Sarah Stein and colleagues for their publication Racial and Ethnic Disparities in Early Mortality among Patients with Inborn Errors of Immunity which is featured in the Journal of Allergy and Clinical Immunology!

Ann Wu and team’s publication “National Patterns of Outpatient Follow-Up Visits After Emergency Care for Acute Bronchiolitis” is featured in JAMA Network Open!

Cheers to Ann Wu and colleagues for their publication “Housing Insecurity and Asthma Outcomes” featured in JACI In Practice!

Ann Wu and colleagues’ paper “Association between antenatal corticosteroid treatment and severe adverse events in pregnant women” is featured in BMC Medicine!

SEPTEMBER

Congrats to Ann and team for their publication “Prevalence and prescribing patterns of oral corticosteroids in the United States, Taiwan, and Denmark, 2009-2018” being featured in Clinical and Translational Science!

Cheers to Davene and peers for their paper “Medicare Part D Coverage of Anti-obesity Medications: a Call for Forward-Looking Policy Reform” featured in the Journal of General Internal Medicine.

Congrats to Ann and Monica for their paper “The Role of Genetic Testing for Short Stature Now and in the Future” featured in JAMA Pediatrics!

Congrats to Davene and colleagues for their publication “Patient Preferences in Diagnostic Imaging: A Scoping Review” being featured in Patient!

Cheers to Isdin and Sharon for their publication “Vision Screening Among Children With Private Insurance: 2010-2019” featured in Pediatrics!

Cheers to Ann Wu and team for their publication “Patterns of Outpatient Follow-up Visits After Hospitalizations for Acute Bronchiolitis” featured in JAMA Pediatrics!

Congrats to Hadley for becoming a Member of the HMS Center for Bioethics!

AUGUST

Congrats to Katherine and team on their paper "Safety Signal Identification for COVID-19 Bivalent Booster Vaccination Using Tree-based Scan Statistics in the Vaccine Safety Datalink" being accepted by Vaccine!

Alon Peltz and colleagues’ paper “Annual Variation in 30-Day Risk-Adjusted Readmission Rates in U.S. Children's Hospitals” is featured in Academic Pediatrics.

Congrats to Mei-Sing Ong and colleagues’ for their paper “Association of inborn errors of immunity with severe COVID-19 and post-acute sequelae of COVID-19” featured in JACI In Practice!

Davene Wright and peers’ publication “Current and Future Challenges Regarding Estimating Costs to Determine the Value of Interventions to Manage Unhealthy Weight” is featured in JAMA Pediatrics!

Hadley Stevens Smith’s paper “Parent-Reported Clinical Utility of Pediatric Genomic Sequencing” is featured in Pediatrics!

Ann Wu and colleagues’ paper “How Likes and Retweets Impacted Our Patients During the COVID-19 Pandemic” is featured in JACI In Practice!

Hadley Stevens Smith is featured in “Conversations With the Editors: Stewardship in Genomic Medicine-Insights From Health Care Payers at the Forefront of Clinical Innovation and Partnerships” in Clinical Therapeutics!

Ann Wu’s paper “Housing Mobility Intervention and the Impact on Pediatric Asthma Morbidity: A Novel Asthma-Directed Therapy” is featured in JACI In Practice!

Hadley Stevens Smith’s paper “Pediatric Genomic Medicine: Value, Implementation, and Access” is featured in Clinical Therapeutics!

Ann Wu and colleagues’ paper “Utilization and Spending With Preventive Drug Lists for Asthma Medications in High-Deductible Health Plans” is featured in JAMA Network Open!

Davene Wright and peers’ publication “Interpreting Cost-Effectiveness Analyses of Anti-Obesity Medications for the Treatment of Adolescent Obesity-Reading the Tea Leaves” is featured in JAMA Network Open!

Ann Wu and colleagues’ paper “Association between antenatal corticosteroids and risk of serious infection in children: nationwide cohort study” is featured in BMJ!

Ann Wu and colleagues’ paper “Polygenic risk scores identify heterogeneity in asthma and chronic obstructive pulmonary disease” is featured in the Journal of Allergy and Clinical Immunology!

Sharon Lutz and peers’ publication “Carriers of rare damaging CCR2 genetic variants are at lower risk of atherosclerotic disease” is featured in medRxiv!

JULY

Welcome to CHeRP Karen Gilbert (Analyst), Ally Geanacopoulos (HSR Fellow), and Ellen Kim DeLuca (DPM fellow)!

Congratulations to CHeRP faculty members on new grant funding:

  • Kurt Christensen for his Robert H. Ebert Career Development Award, "Outcomes Toolkit for Genomic Screening"
  • Davene Wright on her R01 from AHRQ, "Optimizing Choice of Health Insurance for Diabetes"
  • Mei-Sing Ong for her PCORI project, "Learning to predict disease trajectories"

Affiliated CHeRP faculty Isdin Oke and CHeRP faculty Sharon Lutz’s paper “Use and Costs of Instrument-Based Vision Screening for US Children Aged 12 to 36 Months” is featured in JAMA Pediatrics!

Affiliated CHeRP Faculty Isdin Oke and CHeRP faculty Ann Wu’s publication “Improving Estimates of the Geographic Distribution of Pediatric Ophthalmologists to Identify Underserved Regions” is featured in JAMA Ophthalmology!

Hadley Stevens Smith’s paper “The Other Side of the Self-Advocacy Coin: How For-Profit Companies Can Divert the Path to Justice in Rare Disease” is featured in The American Journal of Bioethics!

Congrats to Kurt Christensen, Maddie Hickingbotham and Emilie Zoltick for their publication “Attitudes about pharmacogenomic testing vary by healthcare specialty” featured in Pharmacogenomics!

Kurt Christensen and colleagues’ manuscript “Actionability of unanticipated monogenic disease risks in newborn genomic screening: Findings from the BabySeq Project” is featured in the American Journal of Human Genetics!

Hadley Stevens Smith and Maddie Hickingbotham’s paper “Clinically Indicated Genomic Sequencing of Children in Foster Care: Legal and Ethical Issues” is featured in the Journal of Pediatrics!

Katherine Yih and colleagues’ paper “Safety of simultaneous vaccination with COVID-19 vaccines in the Vaccine Safety Datalink” is featured in Vaccine!

Ann Wu and peers’ paper “Patterns of Outpatient Follow-up Visits After Hospitalizations for Acute Bronchiolitis” is featured in JAMA Pediatrics!

June

Cheers to Hadley Stevens Smith, who has been appointed Assistant Professor of Population Medicine!

Congrats to Sharon Lutz, who has been promoted to Associate Professor of Population Medicine!

Congrats to Davene Wright for being awarded the 2023 Gordon Moore Excellence in Mentoring Award!

Cheers to Jess Leblanc for her nomination for the 2023 Gordon Moore Excellence in Mentoring Award!

CHeRP had guest speaker Dr. Ashley Leech present on "Treatment for Opioid Use Disorder: Optimizing Pregnancy and Birth Outcomes" on June 26, 2023!

Ann Wu, Pamela McMahon and colleagues’ publication The association of varying treatment thresholds of mepolizumab on asthma exacerbations in adults is featured in the Journal of Asthma.

Katherine Yih and colleagues’ publication Safety of simultaneous vaccination with COVID-19 vaccines in the Vaccine Safety Datalink is featured in Vaccine!

Hadley Stevens Smith and colleagues’ publication The Other Side of the Self-Advocacy Coin: How For-Profit Companies Can Divert the Path to Justice in Rare Disease is featured in the American Journal of Bioethics.

Kurt Christensen and colleagues’ publication Actionability of unanticipated monogenic disease risks in newborn genomic screening: Findings from the BabySeq Project is featured in the American Journal of Human Genetics!

Ann Wu and colleagues’ publication Will This Toddler Wheeze Again? Is featured in JACI in Practice!

Sharon Lutz, Marie France Hivert and colleagues’ publication Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age is featured in Clinical Epigenetics!

Alison Galbraith and Ann Wu attended the Pediatric Health Services Research Fellowship Graduation where Isdin Oke, Claire Abraham, and Daniel Shapiro graduated! (Pictured at left, from left to right: Isden Oke, Claire Abraham, Alison Galbraith, Ann Wu, and Daniel Shapiro)

May

Cheers to Alon Peltz and colleagues for their publication Racial and Ethnic Differences in Insurer Classification of Nonemergent Pediatric Emergency Department Visits being featured in JAMA Network Open!

Cheers to Kurt Christensen and colleagues for their publication Public perspective on medications to delay Alzheimer's disease symptom featured in Journal of Genetic Counseling.

Congrats to Isdin Oke and Ann Wu for their publication "Improving Estimates of the Geographic Distribution of Pediatric Ophthalmologists to Identify Underserved Regions" featured in JAMA Ophthamology!

Cheers to Isdin Oke and Sharon Lutz for their publication "Use and Costs of Instrument-Based Vision Screening for US Children Aged 12 to 36 Months" featured in JAMA Pediatrics!

Kurt Christensen, Ann Wu and colleagues’ publication SLCO1B1 gene-based clinical decision support reduces statin-associated muscle symptoms risk with simvastatin is featured in Pharmacogenomics!

Cheers to Mei-Sing for her publication "Association of inborn errors of immunity with severe COVID-19 and post-acute sequelae of COVID-19" featured in JACI In Practice!

Hadley Stevens Smith and colleagues’ publication Cascade testing after exome sequencing: Retrospective analysis of linked family data at 2 US laboratories is featured in Genetics in Medicine!

Cheers to Davene Wright and colleague for their publication "Data is a plural word": large datasets and their use in pediatric imaging research featured in Pediatric Radiology!

Davene and Alison were in Berlin forthe 18th Biennial European Conference SMDM conference!

April



Congrats to Ann Wu and team for receiving funding for their PreEMPT II proposal!

The PreEMPT Study also has a new logo, designed by Mikaela Batista:

Congrats to CHeRP Fellow Isdin Oke for being awarded the Knights Templar Eye Foundation, Inc Career Starter grant for 2023 -2024!

Hadley Stevens Smith attended and presented at the 2023 ACMG Annual Clinical Genetics Meeting!

Cheers to Davene and peers for their publication A Prescription for Achieving Equitable Access to Antiobesity Medications featured in JAMA Health Forum.

Hadley Stevens Smith and colleagues’ publication Key drivers of family-level utility of pediatric genomic sequencing: a qualitative analysis to support preference research is featured in the European Journal for Human Genetics!

Hadley Stevens Smith, Maddie Hickingbotham and colleagues’ publication Framing the Family: A Qualitative Exploration of Factors That Shape Family-Level Experience of Pediatric Genomic Sequencing is featured in Children!

Cheers to Davene and peers for their publication A Prescription for Achieving Equitable Access to Antiobesity Medications featured in JAMA Health Forum.

Hadley Stevens Smith and colleagues’ publication Key drivers of family-level utility of pediatric genomic sequencing: a qualitative analysis to support preference research is featured in the European Journal for Human Genetics!

Hadley Stevens Smith, Maddie Hickingbotham and colleagues’ publication Framing the Family: A Qualitative Exploration of Factors That Shape Family-Level Experience of Pediatric Genomic Sequencing is featured in Children!

March

Cheers to Davene Wright and colleagues for their publication Cost-effectiveness of Dental Workforce Expansion Through the National Health Service Corps and Its Association With Oral Health Outcomes Among US Children featured in JAMA Health Forum!

Hadley Stevens Smith and colleagues’ publication Access to clinically indicated genetic tests for pediatric patients with Medicaid: Evidence from outpatient genetics clinics in Texas is featured in Genetics in Medicine!

Kurt Christensen and colleagues’ publication Parents' decision-making regarding whether to receive adult-onset only genetic findings for their children: Findings from the BabySeq Project is featured in Genetics in Medicine!

CHeRP is thrilled to announce Kirsten Voorhies’ promotion to Senior Biostatistician. This promotion reflects the excellent work and increased responsibilities that Kirsten has taken on. Kirsten demonstrates strong leadership in the development of new statistical methods for use in research projects and takes primary responsibility for and lead authorship on scientific reports. She has made important contributions to the division through her work with Dr. Sharon Lutz, and CHeRP is so happy to see her take on this new role. Congratulations, Kirsten!

Guest speaker Dr. Angela Dixon, PhD presented her seminar “Empty Seats at the Dinner Table: Black-White Disparities in Exposure to Household Member Deaths” on March 27.

February

Congrats to Kurt Christensen, Ann Wu, and colleagues on their publication Benefits, harms, and costs of newborn genetic screening for hypertrophic cardiomyopathy: Estimates from the PreEMPT model being featured in Genetics in Medicine!

The visual abstract was also featured online. Visual abstract designed by Mikaela Batista.

Cheers to Sharon Lutz and colleagues on their publication Integrating Genetics, Transcriptomics, and Proteomics in Lung Tissue to Investigate COPD featured in American Journal of Respiratory Cell and Molecular Biology!

Cheers to Sharon Lutz and colleagues on their publication Clinical Markers Associated With Risk of Suicide or Drug Overdose Among Individuals With Smoking Exposure: A Longitudinal Follow-up Study of the COPDGene Cohort featured in Chest!

Guest speaker Justin Yu, MD, MS presented “Understanding and Improving the Well-Being of Caregivers of Children with Medical Complexity" on February 27.

January

Congratulations to Hadley Stevens Smith on receiving the 2023 Ebert Fellowship! Given annually in memory of Robert H. Ebert, founder of Harvard Community Health Plan and former Dean of Harvard Medical School, the Ebert Fellowship is part of the Harvard Medical School Eleanor and Miles Shore Faculty Development Awards. The fellowship is awarded to junior faculty to support research and career development in population medicine.

CHeRP is delighted that Davene Wright has agreed to serve as Associate Director. Since joining CHeRP in 2019, she has made substantial contributions to CHeRP and to the department - from research in decision sciences, to best practices in DEI hiring and to developing your personal brand! Congratulations and thank you!

CHeRP is excited to announce Ryan Walsh’s promotion to Senior Administrative/Project Specialist. This promotion reflects Ryan’s increased administrative and project responsibilities, and the excellent work and leadership that he demonstrates in leading pre-award processes for multiple faculty members, supporting projects for the division, and mentoring new administrative staff. Ryan is a crucial part of the CHeRP team and we are so happy to see his growth in the division. Congratulations, Ryan!

Hadley Stevens Smith received a DPM Faculty Grant, for her project titled, Health care utilization among families of children with genetic conditions.

CHeRP had guest speaker, Dr. Rebecca Delaney, present “Facing the Impossible: Development and Evaluation of a Decision Aid for Severe Congenital Heart Disease” at our 1/23/23 CHeRP Seminar.

Publications:
Alon Peltz and colleagues’ publication Food Insecurity Was Associated With Greater Family Health Care Expenditures In The US, 2016-17 is featured in Health Affairs.

Sharon Lutz and colleagues’ publication A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets is featured in Briefings in Bioinformatics.

Katherine Yih and Judy Maro’s publication A broad assessment of covid-19 vaccine safety using tree-based data-mining in the vaccine safety datalink is featured in Vaccine.

Kurt Christensen and colleagues’ publication Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos is featured in HGG Advances.

Davene Wright and colleagues’ publication Student-Athlete Preferences for Sexual Violence Reporting: A Discrete Choice Experiment is featured in The Patient.

Alon Peltz’ article Measuring health disparities using a continuous social risk factor is featured in Health Services Research!

Ann Wu and colleagues’ article Teleallergy: Where Have We Been and Where Are We Going? is featured in JACI In Practice.