Christine Lu MSc, PhD is an Associate Professor in the Department of Population Medicine at Harvard Medical School and Harvard Pilgrim Health Care Institute and she co-directs the PRecisiOn Medicine Translational Research (PROMoTeR) Center. She is a pharmacist, health policy scientist and pharmacoepidemiologist. After receiving an MSc (Biopharmaceuticals) and a PhD in Clinical Pharmacology from the University of New South Wales, Australia, Dr. Lu completed her post-doctoral training at Harvard Medical School.
Dr. Lu leads the precision medicine & policy, and precision medicine oncology portfolios for the DPM. Her research focuses on the policy, legal, ethical, economic and societal issues of precision medicine, which have substantial impacts on the coverage and reimbursement and clinical integration of genomic testing and sequencing. She is Co-Principal Investigator of Genomics-based Technologies: Access and Reimbursement Issues. Dr. Lu co-leads the Genetic and Molecular Tests Data Workgroup for the Cancer Research Network. She is site Principal Investigator of an NCI-funded project to examine organizational and economic barriers and facilitators to the implementation of universal Lynch Syndrome Screening across multiple healthcare systems (Study PI: Alanna Rahm, Geisinger Health). She also conducts research to assess real-world utility of genomic testing and sequencing, including the impact of value-based contracts. Dr. Lu provides intense one-on-one mentorship to PhD students, post-doctoral students, researchers, and mid-career university faculty. Please direct inquiries about fellowships and training opportunities relating to precision medicine research to Dr. Lu.
Dr. Lu has contributed substantially to evaluations of health policies in developing and developed countries using large, longitudinal administrative healthcare data and rigorous quasi-experimental research methods. Dr. Lu led a national investigation of the effects of Food and Drug Administration‘s warnings and media attention regarding antidepressant and suicidality among youth. She received an Early Career Investigator award from the national Health Care Systems Research Network for this work. Dr. Lu is Co-Principal Investigator of a PCORI project (IHS-1408-20393) examining effects of high-deductible insurance plans on patients with bipolar disorder and an investigator of another four major projects assessing the impact of high-deductible insurance on appropriate health care.
Since 2003, Dr. Lu has examined access to high-cost specialty drugs (i.e., biologics for rare and chronic conditions including cancer, rheumatoid arthritis, hepatitis C, and rare diseases). She is the lead investigator of an international study of managed entry agreements for such drugs. Dr. Lu is the lead of a national study examining reimbursement of direct acting antivirals for chronic hepatitis C under state Medicaid programs, and the Principal Investigator of a regional study examining approaches for managing the use of direct acting antivirals for chronic hepatitis C.
Dr. Lu is an investigator of the Cancer Research Network and the Mental Health Research Network, the Health Care Systems Research Network. She also serves as a pharmacoepidemiologist for the FDA-funded Sentinel System, a congressionally mandated national medical product safety surveillance system.